By Steven W. Cranford, Markus J. Buehler (auth.)
Biomateriomics is the holistic examine of organic fabric structures. whereas such structures are definitely complicated, we often come across comparable parts -- common development blocks and hierarchical constitution motifs -- which bring about a various set of functionalities. just like the way in which tune or language arises from a restricted set of song notes and phrases, we take advantage of the relationships among shape and serve as in a significant method by means of spotting the similarities among Beethoven and bone, or Shakespeare and silk. in the course of the research of fabric homes, interpreting primary hyperlinks among methods, constructions, and homes at a number of scales and their interactions, materiomics explains approach performance from the extent of establishing blocks.
Biomateriomics particularly focuses the research of the function of fabrics within the context of organic approaches, the move of organic fabric rules in the direction of biomimetic and bioinspired functions, and the learn of interfaces among dwelling and non-living structures. The demanding situations of organic fabrics are immense, however the convergence of biology, arithmetic and engineering in addition to computational and experimental concepts have ended in the toolset essential to describe complicated fabric structures, from nano to macro. employing biomateriomics can free up Nature’s mystery to excessive functionality fabrics similar to spider silk, bone, and nacre, and elucidate the development and analysis or the remedy of illnesses. equally, it contributes to increase a de novo figuring out of organic fabric tactics and to the possibility of exploiting novel innovations in innovation, fabric synthesis and design.
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Extra info for Biomateriomics
32 2 The Materiome of non-biological systems in which emergence plays a role include social networks, ancient and modern cultures, languages and writing systems, and economies and ecosystems. Recently, the “omic” approach has found a particularly fitting niche within the field of integrative biology—the study and research of biological systems from a biological science, engineering and physical science perspective. Specific research may involve genetics or environmental studies, yet the goal is always to solve a larger, biological problem—from the smallest, molecular studies to broader studies of the biosphere [12, 13].
N). The cycle initiates at H0 (process H0 , the only level at which protein expression occurs) to form protein constituents (structure H0 ). Their properties (property H0 ) control the association at the next hierarchical level (process H1 leading to structure H1 ). This cycle continues through all hierarchical levels i = 0 . . N, where process and structure H1 and beyond denote protein assembly stages. At each stage, the properties of the structure control the assembly at the next level. Overall, properties at different hierarchical levels (properties Hi ) are regulated by corresponding physiologic demands (requirements Ri ), which are sensed and transduced intracellularly to activate genetic regulation, resulting in changes to process H0 .
In other words, the materiome changes. , strength or mass), early insights further linked biological processes—such as walking, running, and the flight of birds—using a mechanistic framework (see Fig. 2). It was a radical paradigm that all living systems, including the human body, could be described as simple machines ruled by the same mechanical laws. More recently, the works of Steven Vogel [2–6] has introduced the field of comparative biomechanics—application of biomechanics to non-human organisms and reducing the biomechanical universe to a set of simple tubes, surfaces, flows, beams, and levers, all amenable to simple calculation and estimation.
Biomateriomics by Steven W. Cranford, Markus J. Buehler (auth.)